Weighing in here...
I can only tell you my somewhat limited experiences so far.
The Wilwood calipers work very well on my car, which is just under 3000lbs with me in it. They will work the road course all weekend, and have been great on the street too. Anyone who has had a ride can tell you that these brakes are serious business.
I got 4 track events and about 12k miles out of the first set of pads (Polymatrix D pads, would have gone longer on street, but had to switch for track inspection - just below 1/4" thick), and I have just started the second set. My guess is that the pads would be good for at least 20-30k miles without racing, which takes a big toll.
I've driven in heavy rain many times and on a few dirt roads, and the caliper pistons looked fine when I swapped pads this spring. I think the lack of dust seals is overplayed, unless you are driving in extreme dusty conditions or winter.
Of course, if the Viper calipers are similar price or not too much more, then they are probably a better choice for a pure street car.
Happy stopping,
Lou